The purpose of this study was examination of emotional problems and coping styles in children with Acute Lymphoblastic Leukemia and compared with healthy children. Fifty-five children hospitalized at Children's Hospital in the Cancer and Blood Ward and frothy-five healthy children who referred to vaccination were participated in this study. Participants were compared to each other in the “Evaluation of the Child Drawing: Hospital Manual” and “Koppitz’s Emotional Indicators” in the drawing injection picture. Results showed a significant difference between cancer and healthy children in all subscales of Evaluation of the Child Drawing: Hospital Manual. Furthermore, participants in both groups were compared in Koppitz’s Emotional Indicators. Differences between the groups in the use of black color, small paint, shaded face, body, hands and unusual images were significant. Results showed that children with Leukemia were more use of avoidance strategies while healthy children applied approaching strategies. In addition, based on Koppitz’s indicators, children with Leukemia were demonstrated more emotional problems. These findings help to health providers to design clinical interventions for children with cancer

Keywords: child, Acute Lymphoblastic Leukemia, Coping style, emotional indicators, drawing